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ET receptor antagonist 2

Compound 16j is a potent, orally bioavailable endothelin receptor antagonist with an IC50 of 0.22 nM. It is a valuable research tool for pulmonary arterial hypertension, demonstrated to ameliorate disease progression in monocrotaline-induced rat models of PAH.

Product Specifications

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Molecular Formula

C22H25N5O5S

Molecular Weight

471.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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