ET receptor antagonist 3
Compound 17d is a potent, orally bioavailable endothelin receptor antagonist with an IC50 of 0.26 nM. It is a valuable research tool for pulmonary arterial hypertension (PAH), demonstrating in vivo efficacy in ameliorating monocrotaline-induced PAH in rat models.
Product Specifications
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C27H28N6O5S
Molecular Weight
548.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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