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HCA/VEGFR-2-IN-4

HCA/VEGFR-2-IN-4 (15b) is a dual-action indolinylbenzenesulfonamide inhibitor with potent activity against cancer-associated hCA IX/XII (Ki values in low nM range) and VEGFR-2 (IC50 = 0.811 μM) . It demonstrates antiproliferative effects in breast cancer cell models, supporting its investigation in oncology research for targeting tumor hypoxia and angiogenesis.

Product Specifications

Field of Research

Cardiovascular Research, Cardiovascular Research; Cell Biology, Metabolism Research, Signal Transduction

Molecular Formula

C22H23FN6O5S

Molecular Weight

502.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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