MS9715
MS9715 is a potent and selective PROTAC degrader of NSD3, constructed from a BI-9321-derived PWWP1 domain binder and a VHL E3 ligase ligand. It serves as a valuable chemical probe for investigating NSD3 biology and its therapeutic potential in cancers, supporting both in vitro and in vivo degradation studies.
Product Specifications
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
CC1=CC (CNCCCC (NCCCCCCCCC (N[C@@H] (C (C) (C) C) C (N2[C@H] (C (N[C@@H] (C) C3=CC=C (C4=C (C) N=CS4) C=C3) =O) C[C@@H] (O) C2) =O) =O) =O) =CC (C) =C1C5=C (C6=CC=NC7=C6C=CC (F) =C7) N (C) C=N5
Molecular Formula
C58H74FN9O5S
Molecular Weight
1028.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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