YL-109
YL-109 is an antitumor agent that can induce carboxyl terminus of Hsp70-interacting protein (CHIP) expression through aryl hydrocarbon receptor (AhR) signaling. YL-109 has ability to inhibit breast cancer cell growth and invasiveness[1].
Product Specifications
CAS Number
36341-25-0
UNSPSC
12352005
Hazard Statement
H315, H317, H318, H334, H335, H341, H361, H370, H413
Target
Aryl Hydrocarbon Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/YL-109.html
Purity
99.26
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C2=NC3=CC=CC=C3S2)C=C1OC
Molecular Formula
C14H11NO2S
Molecular Weight
257.31
Precautions
H315, H317, H318, H334, H335, H341, H361, H370, H413
References & Citations
[1]Hiyoshi H, et al. 2- (4-Hydroxy-3-methoxyphenyl) -benzothiazole suppresses tumor progression and metastatic potential of breast cancer cells by inducing ubiquitin ligase CHIP. Sci Rep. 2014 Nov 18;4:7095.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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