YL-109

YL-109 is an antitumor agent that can induce carboxyl terminus of Hsp70-interacting protein (CHIP) expression through aryl hydrocarbon receptor (AhR) signaling. YL-109 has ability to inhibit breast cancer cell growth and invasiveness[1].

Product Specifications

CAS Number

[36341-25-0]

UNSPSC

12352005

Hazard Statement

H315, H317, H318, H334, H335, H341, H361, H370, H413

Target

Aryl Hydrocarbon Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/YL-109.html

Purity

99.26

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C2=NC3=CC=CC=C3S2)C=C1OC

Molecular Formula

C14H11NO2S

Molecular Weight

257.31

Precautions

H315, H317, H318, H334, H335, H341, H361, H370, H413

References & Citations

[1]Hiyoshi H, et al. 2- (4-Hydroxy-3-methoxyphenyl) -benzothiazole suppresses tumor progression and metastatic potential of breast cancer cells by inducing ubiquitin ligase CHIP. Sci Rep. 2014 Nov 18;4:7095.