PKM2-IN-4
Pkm2-in-4 (Compound 5C) is a selective PKM2 inhibitor (IC50 = 0.35 μM) that alters cellular metabolism by suppressing pyruvate-driven respiration. This action enhances mitochondrial hydrogen peroxide generation and improves electron transport chain coupling, making it a useful tool for studying cancer metabolism and oxidative stress in vitro.
Product Specifications
Field of Research
Metabolism Research
Molecular Formula
C15H17BrClNO3Se
Molecular Weight
453.62
Storage Conditions
-20°C
Notes
For research use only.
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