VEGFR/PARP-IN-1

VEGFR/PARP-IN-1 (Compound 14b) is a dual VEGFR and PARP inhibitor with IC50 values of 191 nM and 60.9 nM, respectively. It exhibits antiproliferative activity in BRCA wild-type breast cancer cell lines (e.g., MDA-MB-231, MCF-7) by inducing cell cycle arrest and apoptosis, supporting its investigation in oncology research for potential antitumor effects.