PI3Kδ-IN-14

PI3Kδ-IN-14 is a potent and selective PI3Kδ inhibitor (IC50=0.8 nM) that binds the kinase's ATP-binding site. It blocks the PI3K/AKT signaling pathway, demonstrating anti-inflammatory effects and efficacy in models of acute lung injury, making it a valuable tool for immunology and inflammation research.