RUNX-IN-2
RUNX-IN-2 is a covalent small molecule inhibitor that selectively alkylates RUNX-binding DNA sequences. This activity disrupts RUNX function, leading to inhibition of cancer cell proliferation and p53-dependent apoptosis, as demonstrated in both in vitro assays and in vivo PANC-1 xenograft models.
Product Specifications
CAS Number
2893777-88-1
Field of Research
Cell Biology
Smiles
N (C (=O) C1=NC (NC (=O) C2=NC (NC (CCNC (CCCC3=CC=C (N (CCCl) CCCl) C=C3) =O) =O) =CN2C) =CN1C) C=4C=C (C (NC=5N=C (C (NCCCC (NC=6C=C (C (NC=7C=C (C (NC=8C=C (C (NC=9C=C (C (NCCCN (C) C) =O) N (C) C9) =O) N (C) C8) =O) N (C) C7) =O) N (C) C6) =O) =O) N (C) C5) =O) N (C) C4
Molecular Formula
C71H88Cl2N24O11
Molecular Weight
1524.52
Storage Conditions
-20°C
Notes
For research use only.
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View Details MBS627773-02 5x 0.2 mL
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