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PSEN1-IN-2

PSEN1-IN-2 (Compound 13K) is a highly potent, selective inhibitor of γ-secretase, specifically targeting both PSEN1-APH1A and PSEN1-APH1B complexes with IC50 values of 6.9 nM and 2.4 nM, respectively. This small molecule is a valuable chemical tool for Alzheimer's disease research, enabling mechanistic studies of amyloid precursor protein processing in cellular and biochemical assays.

Product Specifications

Field of Research

Cell Biology, Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Molecular Formula

C20H18ClFN2O3S

Molecular Weight

420.88

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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