PSEN1-IN-2
PSEN1-IN-2 (Compound 13K) is a highly potent, selective inhibitor of γ-secretase, specifically targeting both PSEN1-APH1A and PSEN1-APH1B complexes with IC50 values of 6.9 nM and 2.4 nM, respectively. This small molecule is a valuable chemical tool for Alzheimer's disease research, enabling mechanistic studies of amyloid precursor protein processing in cellular and biochemical assays.
Product Specifications
Field of Research
Cell Biology, Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Molecular Formula
C20H18ClFN2O3S
Molecular Weight
420.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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