FAK-IN-11

FAK-IN-11 (Compound 4l) is a selective focal adhesion kinase (FAK) inhibitor that binds the ATP pocket to block autophosphorylation. It demonstrates cytotoxic activity against MDA-MB-231 breast cancer cells with an IC50 of 13.73 μM, inducing a form of non-apoptotic cell death, which supports its use in oncology research for studying FAK signaling in vitro.