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SIRT6-IN-3

SIRT6-IN-3 (8a) is a selective SIRT6 inhibitor (IC50 = 7.49 μM) that suppresses proliferation and induces apoptosis in pancreatic ductal adenocarcinoma (PDAC) cells. It synergizes with gemcitabine by inhibiting DNA damage repair, making it a useful chemical probe for studying pancreatic cancer biology in vitro.

Product Specifications

CAS Number

3023471-40-8

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Smiles

[Br-].Cl.BrC=1C=C (NC1Br) C2=NC=CC3=C2N=CN3CCCCCCSC (N (C) C) =[N+] (C) C

Molecular Formula

C21H30Br3ClN6S

Molecular Weight

673.73

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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