TRK-IN-24
TRK-IN-24 is a potent and selective small molecule inhibitor of Trk receptors, including wild-type TRKA, TRKC, and key resistance mutants such as G595R and G667C. It demonstrates robust anti-proliferative activity in cellular assays and exhibits significant antitumor efficacy in relevant xenograft models, supporting its use in oncology research targeting NTRK-driven cancers.
Product Specifications
CAS Number
2937544-01-7
Field of Research
Signal Transduction
Smiles
O=C1C2=NN3C (=CN=C3C=C2) C#CC4=C (C) C (C (NC5=CC (=CC (CN6CCN (C) CC6) =C5) C7CC7) =O) =CC (=C4) OCCCCCCCN1
Molecular Formula
C39H45N7O3
Molecular Weight
659.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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