VHL-IN-1
VHL-IN-1 is a potent VHL E3 ligase inhibitor with a 37 nM Kd, effectively stabilizing HIF-1α and augmenting its transcriptional function. This small molecule is a valuable chemical probe for hypoxia research and serves as a foundational component for developing PROTAC degraders in both cellular and animal studies.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C28H37FN4O4S
Molecular Weight
544.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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