RET-IN-25
RET-IN-25 (6b) is a potent and selective RET kinase inhibitor effective against medullary thyroid carcinoma. It demonstrates consistent inhibitory activity in TT (C634R) MTC cells with IC50 values of 3.6 μM (3-day) and 3.0 μM (6-day) . This compound is a valuable research tool for investigating RET-driven cancers in both in vitro and in vivo models.
Product Specifications
CAS Number
2965703-02-8
Field of Research
Cell Biology, Signal Transduction
Smiles
O=[N+] (C1=CC=C (N=C2) C (C3=C2C (NC (C4=CC=C (C=C4) C) =O) =C (C (OCC) =O) S3) =C1) [O-]
Molecular Formula
C22H17N3O5S
Molecular Weight
435.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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