BRD4 Inhibitor-10

BRD4 Inhibitor-10 is a potent BRD4-BD1 inhibitor extracted from patent WO2015022332A1, Compound II-25, has an IC50 of 8 nM[1].

Epigenetic Reader Domain

Reference compound

Epigenetics

Cancer

https://www.medchemexpress.com/brd4-inhibitor-10.html

99.52

DMSO : 125 mg/mL (ultrasonic)

CN1C(C(C)=CC(C2=NC3=CN=C(C=C3N2[C@H](C4=CC=CC=C4)C)C5CCOCC5)=N1)=O

429.51

[1]Harald Engelhardt, et al. Pyridinones. WO2015022332A1.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-117491/BRD4-Inhibitor-10-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-117491/BRD4-Inhibitor-10-SDS-MedChemExpress.pdf

Phase 1

1660117-38-3