BRD4 Inhibitor-10
BRD4 Inhibitor-10 (Compound II-25) is a potent BRD4-BD1 inhibitor with an IC50 of 8 nM. BRD4 Inhibitor-10 can be used to study diseases caused by abnormal or excessive cell proliferation, such as cancer[1].
Product Specifications
CAS Number
[1660117-38-3]
UNSPSC
12352005
Hazard Statement
H302, H319, H332, H372, H400
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd4-inhibitor-10.html
Purity
99.52
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CN1C(C(C)=CC(C2=NC3=CN=C(C=C3N2[C@H](C4=CC=CC=C4)C)C5CCOCC5)=N1)=O
Molecular Formula
C25H27N5O2
Molecular Weight
429.51
Precautions
H302, H319, H332, H372, H400
References & Citations
[1]Harald Engelhardt, et al. Pyridinones. WO2015022332A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
BRD4
Available Sizes
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