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LB244

LB244 is an orally bioavailable small molecule STING inhibitor with an EC50 of 0.8 μM. It is a functional analogue of BB-Cl-amidine, useful for studying STING-driven inflammation in cellular assays, though its oral bioavailability in mouse models is limited.

Product Specifications

CAS Number

3074622-05-9

Field of Research

Immunology & Inflammation

Smiles

O=C (C1=CC=C (C2=CC=CC=C2) C=C1) N[C@H] (C3=NC4=CC=CC=C4N3) CCCCNC (C5=CC=C ([N+] ([O-]) =O) O5) =O

Molecular Formula

C30H27N5O5

Molecular Weight

537.57

Storage Conditions

-20°C

Notes

For research use only.

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