LB244
LB244 is an orally bioavailable small molecule STING inhibitor with an EC50 of 0.8 μM. It is a functional analogue of BB-Cl-amidine, useful for studying STING-driven inflammation in cellular assays, though its oral bioavailability in mouse models is limited.
Product Specifications
CAS Number
3074622-05-9
Field of Research
Immunology & Inflammation
Smiles
O=C (C1=CC=C (C2=CC=CC=C2) C=C1) N[C@H] (C3=NC4=CC=CC=C4N3) CCCCNC (C5=CC=C ([N+] ([O-]) =O) O5) =O
Molecular Formula
C30H27N5O5
Molecular Weight
537.57
Storage Conditions
-20°C
Notes
For research use only.
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