BQZ-485
BQZ-485 is a potent and selective GDI2 inhibitor that disrupts the GDI2-Rab1A interaction by targeting Tyr245. This inhibition blocks ER-to-Golgi vesicular transport, inducing paraptosis, and serves as a valuable chemical probe for studying intracellular trafficking and cell death mechanisms in cancer research.
Product Specifications
CAS Number
1906915-49-8
Field of Research
Cell Biology
Smiles
O (CC1=CC (C) =CC (C) =C1) C=2C=C3[C@@]4 (N (CCC3=CC2OCC5=CC (C) =CC (C) =C5) [C@@H] (C) C[C@H] (O) C4) [H]
Molecular Formula
C32H39NO3
Molecular Weight
485.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Mouse Monoclonal DDR2 Antibody (290804) [PerCP]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
GTR15185980 1 Vial
Lentiviral mouse Wasf2 shRNA (UAS) - Lentiviral mouse Wasf2 shRNA (UAS, iRFP) plasmid
Sign In for Pricing
View Details MBS6311102-01 0.2 mL
ISOC2, CT (ISOC2, Isochorismatase domain-containing protein 2, mitochondrial) (PE)
Sign In for Pricing
View Details