BQZ-485
BQZ-485 is a potent and selective GDI2 inhibitor that disrupts the GDI2-Rab1A interaction by targeting Tyr245. This inhibition blocks ER-to-Golgi vesicular transport, inducing paraptosis, and serves as a valuable chemical probe for studying intracellular trafficking and cell death mechanisms in cancer research.
Product Specifications
CAS Number
1906915-49-8
Field of Research
Cell Biology
Smiles
O (CC1=CC (C) =CC (C) =C1) C=2C=C3[C@@]4 (N (CCC3=CC2OCC5=CC (C) =CC (C) =C5) [C@@H] (C) C[C@H] (O) C4) [H]
Molecular Formula
C32H39NO3
Molecular Weight
485.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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