TNIK&MAP4K4-IN-1

TNIK&MAP4K4-IN-1 (A-39) is a potent dual inhibitor of TNIK and MAP4K4, with IC50 values of 1.29 nM and <10 nM, respectively, in LX-2 cells. This small molecule is a valuable research tool for investigating pathways in oncology and fibrotic diseases, including liver fibrosis, in both cellular and animal models.