TNIK&MAP4K4-IN-1
TNIK&MAP4K4-IN-1 (A-39) is a potent dual inhibitor of TNIK and MAP4K4, with IC50 values of 1.29 nM and <10 nM, respectively, in LX-2 cells. This small molecule is a valuable research tool for investigating pathways in oncology and fibrotic diseases, including liver fibrosis, in both cellular and animal models.
Product Specifications
CAS Number
2478592-86-6
Field of Research
Neuroscience, Signal Transduction
Smiles
C (NC=1C (OC) =CN=CC1) (=O) C=2OC (C3=C (N=CN3C4CCCC4) C5=CC=C (F) C=C5) =CC2
Molecular Formula
C25H23FN4O3
Molecular Weight
446.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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