Pan-KRAS-IN-2
Pan-KRAS-IN-2 is a potent, broad-spectrum KRAS inhibitor effective at nanomolar concentrations against wild-type KRAS and multiple G12 and Q61H mutants. It exhibits markedly weaker activity against the G13D mutant. This compound is a valuable chemical probe for investigating KRAS-driven cancers in both cellular and animal model studies.
Product Specifications
CAS Number
2882825-14-9
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (OC=1N=C (C2=C (N1) C (C) =C (C=C2) C=3C4=C (C=C (O) C3) C=CC (F) =C4C#C) N5CCCOCC5) [C@@]67N (C[C@H] (F) C6) CCC7
Molecular Formula
C34H34F2N4O3
Molecular Weight
584.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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