SMD-3040
SMD-3040 is a potent and selective SMARCA2 PROTAC degrader with a DC50 of 12 nM. It achieves robust SMARCA2 degradation over SMARCA4 and has demonstrated significant tumor growth inhibition in xenograft models, supporting its use in oncology and targeted protein degradation research.
Product Specifications
CAS Number
3033109-92-8
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
99.91% (May vary between batches)
Smiles
C (N1CC2 (C1) CCC (CC2) N3C=C (C=N3) C=4C=C (N=NC4N) C5=C (O) C=CC=C5) [C@H]6CC[C@H] (C (N[C@H] (C (=O) N7[C@H] (C (N[C@@H] (C) C8=CC=C (C=C8) C9=C (C) N=CS9) =O) C[C@@H] (O) C7) C (C) (C) C) =O) CC6
Molecular Formula
C52H66N10O5S
Molecular Weight
943.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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