PROTAC MLKL Degrader-1
Compound 36 (PROTAC MLKL Degrader-1) is a potent and selective degrader of MLKL, utilizing a CRBN-recruiting ligand to achieve over 90% degradation. It effectively blocks necroptotic cell death in cellular models, such as TSZ-induced necroptosis, providing a valuable chemical tool for studying programmed necrosis pathways.
Product Specifications
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C46H55F2N9O9S
Molecular Weight
948.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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