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PROTAC MLKL Degrader-1

Compound 36 (PROTAC MLKL Degrader-1) is a potent and selective degrader of MLKL, utilizing a CRBN-recruiting ligand to achieve over 90% degradation. It effectively blocks necroptotic cell death in cellular models, such as TSZ-induced necroptosis, providing a valuable chemical tool for studying programmed necrosis pathways.

Product Specifications

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C46H55F2N9O9S

Molecular Weight

948.05

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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