Irpagratinib
Irpagratinib (ABSK011) is a potent and orally bioavailable FGFR4 inhibitor that suppresses autophosphorylation and downstream signaling. It demonstrates antitumor activity in preclinical models and is used in research targeting cancers, particularly hepatocellular carcinoma and other gastrointestinal malignancies.
Product Specifications
CAS Number
2230974-62-4
Product Name Alternative
ABSK 011, ABSK011
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.08% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.78 mM) ; DMSO:80 mg/mL (140.21 mM)
Smiles
N (C1=NC=2C (=NC (=CC2C=N1) C3=C (F) C (OC) =CC (OC) =C3F) N4CC (OC) (C) C4) [C@H]5[C@@H] (NC (C=C) =O) CCOC5
Molecular Formula
C28H32F2N6O5
Molecular Weight
570.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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