TIE-2/VEGFR-2 kinase-IN-3
TIE-2/VEGFR-2 kinase-IN-3 is a potent benzimidazole-based dual inhibitor of TIE-2 and VEGFR-2 tyrosine kinases with IC50 values of 6.9 nM and 3.5 nM, respectively. It is a valuable research tool for studying angiogenesis and related pathways in both cellular and animal models of cancer and vascular diseases.
Product Specifications
CAS Number
433224-09-0
Field of Research
Cardiovascular Research, Cardiovascular Research; Cell Biology, Signal Transduction
Smiles
N (C (OC) =O) C=1NC=2C (N1) =CC=C (SC3=CC=C (NC (NC4=CC (C (F) (F) F) =CC=C4F) =O) C=C3) C2
Molecular Formula
C23H17F4N5O3S
Molecular Weight
519.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog