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TIE-2/VEGFR-2 kinase-IN-3

TIE-2/VEGFR-2 kinase-IN-3 is a potent benzimidazole-based dual inhibitor of TIE-2 and VEGFR-2 tyrosine kinases with IC50 values of 6.9 nM and 3.5 nM, respectively. It is a valuable research tool for studying angiogenesis and related pathways in both cellular and animal models of cancer and vascular diseases.

Product Specifications

CAS Number

433224-09-0

Field of Research

Cardiovascular Research, Cardiovascular Research; Cell Biology, Signal Transduction

Smiles

N (C (OC) =O) C=1NC=2C (N1) =CC=C (SC3=CC=C (NC (NC4=CC (C (F) (F) F) =CC=C4F) =O) C=C3) C2

Molecular Formula

C23H17F4N5O3S

Molecular Weight

519.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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