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TIE-2/VEGFR-2 kinase-IN-4

TIE-2/VEGFR-2 kinase-IN-4 is a potent benzimidazole-based dual inhibitor of TIE-2 and VEGFR-2 tyrosine kinases, with IC50 values of 5.2 nM and 5.1 nM, respectively. It is a valuable research tool for studying angiogenesis and related pathways in both cellular and animal models of cancer and vascular diseases.

Product Specifications

CAS Number

433224-29-4

Field of Research

Cardiovascular Research, Cardiovascular Research; Cell Biology, Signal Transduction

Smiles

N (C (=O) C1=CC=CO1) C=2NC=3C (N2) =CC=C (OC4=CC=C (NC (NC5=CC (C (F) (F) F) =CC=C5F) =O) C=C4) C3

Molecular Formula

C26H17F4N5O4

Molecular Weight

539.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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