TIE-2/VEGFR-2 kinase-IN-4
TIE-2/VEGFR-2 kinase-IN-4 is a potent benzimidazole-based dual inhibitor of TIE-2 and VEGFR-2 tyrosine kinases, with IC50 values of 5.2 nM and 5.1 nM, respectively. It is a valuable research tool for studying angiogenesis and related pathways in both cellular and animal models of cancer and vascular diseases.
Product Specifications
CAS Number
433224-29-4
Field of Research
Cardiovascular Research, Cardiovascular Research; Cell Biology, Signal Transduction
Smiles
N (C (=O) C1=CC=CO1) C=2NC=3C (N2) =CC=C (OC4=CC=C (NC (NC5=CC (C (F) (F) F) =CC=C5F) =O) C=C4) C3
Molecular Formula
C26H17F4N5O4
Molecular Weight
539.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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