JAK-IN-31
JAK-IN-31 is a potent pan-JAK inhibitor with IC50 values ≤0.01 μM against JAK1, JAK2, and Tyk2, and 0.01-0.1 μM for JAK3. It is a valuable research tool for investigating JAK/STAT signaling in oncology, supporting both in vitro cellular assays and in vivo preclinical studies in cancer models.
Product Specifications
CAS Number
2597016-88-9
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
N (C=1C (=CN=C2C1C=CN2) C=3SC (C) =NN3) [C@@H]4C[C@H] (NS (=O) (=O) C5=CC (C#N) =CC=C5) C4
Molecular Formula
C21H19N7O2S2
Molecular Weight
465.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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