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Cbl-b-IN-9

Cbl-b-IN-9 (Compound 300) is a potent dual inhibitor of Cbl-b and c-Cbl with IC50 values of 5.6 nM and 4.7 nM, respectively. This small molecule is a valuable research tool for investigating E3 ubiquitin ligase function in immunology and oncology, supporting both in vitro biochemical assays and in vivo disease model studies.

Product Specifications

CAS Number

2815223-41-5

Field of Research

Cancer Biology, Protein Biochemistry

Smiles

C (C1 (COC1) C=2C=C (N=C (C2) C3CC3) N4CC=5C (C4=O) =CC (CNC6 (C) CCC6) =CC5C (F) (F) F) C=7N (C) C=NN7

Molecular Formula

C30H33F3N6O2

Molecular Weight

566.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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