Cbl-b-IN-9
Cbl-b-IN-9 (Compound 300) is a potent dual inhibitor of Cbl-b and c-Cbl with IC50 values of 5.6 nM and 4.7 nM, respectively. This small molecule is a valuable research tool for investigating E3 ubiquitin ligase function in immunology and oncology, supporting both in vitro biochemical assays and in vivo disease model studies.
Product Specifications
CAS Number
2815223-41-5
Field of Research
Cancer Biology, Protein Biochemistry
Smiles
C (C1 (COC1) C=2C=C (N=C (C2) C3CC3) N4CC=5C (C4=O) =CC (CNC6 (C) CCC6) =CC5C (F) (F) F) C=7N (C) C=NN7
Molecular Formula
C30H33F3N6O2
Molecular Weight
566.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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