Cbl-b-IN-11
Cbl-b-IN-11 (Compound 466) is a potent dual inhibitor of the E3 ubiquitin ligases Cbl-b and c-Cbl, with IC50 values of 6.4 nM and 6.1 nM, respectively. This small molecule is a valuable research tool for investigating immune regulation and oncogenic signaling pathways in both cellular and animal models.
Product Specifications
CAS Number
2815225-15-9
Field of Research
Cancer Biology, Protein Biochemistry
Smiles
C (C1 (CC (F) (F) C1) C2=CC (=CC (NCC) =C2) N3CC=4C (C3=O) =CC (CNC5 (C) CCC5) =CC4C (F) (F) F) C=6N (C) C=NN6
Molecular Formula
C31H35F5N6O
Molecular Weight
602.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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