Cbl-b-IN-12
Cbl-b-IN-12 is a potent small molecule inhibitor of the E3 ubiquitin ligase CBL-B, exhibiting an IC50 value below 100 nM. This compound is a valuable research tool for investigating CBL-B's role in immune cell signaling and has been utilized in both cellular and animal studies to explore T-cell activation and potential immunotherapeutic applications.
Product Specifications
CAS Number
2851871-29-7
Field of Research
Cancer Biology, Protein Biochemistry
Smiles
C (C1 (COC1) C2=CC (=CC=C2) N3C=C4N (C3=O) C=C (CN5CC6 (CC5) CC6) C=C4C (F) (F) F) C=7N (C) C=NN7
Molecular Formula
C28H29F3N6O2
Molecular Weight
538.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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