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NSC309401

NSC309401 is a potent small molecule inhibitor of E. coli dihydrofolate reductase (DHFR), exhibiting an IC50 of 189 nM and a KD of 14.57 nM. This compound serves as a valuable research tool for studying bacterial folate metabolism and antibiotic resistance mechanisms in both biochemical and cellular assays.

Product Specifications

CAS Number

750522-61-3

Field of Research

Infectious Disease & Virology

Smiles

C (N1C2=C (C=3C (C=C2) =NC (N) =NC3N) C=C1) C4=CC=C (N) C=C4

Molecular Formula

C17H16N6

Molecular Weight

304.35

Storage Conditions

-20°C

Notes

For research use only.

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