6,6′-Dihydroxythiobinupharidine
This small molecule is a cysteine protease inhibitor that potently enhances human topoisomerase IIα and IIβ-mediated DNA cleavage by approximately 8-fold and 3-fold, respectively. It is a valuable research tool for investigating topoisomerase II function and DNA damage mechanisms in biochemical and cellular studies.
Product Specifications
CAS Number
30343-70-5
Field of Research
Protein Biochemistry
Smiles
O[C@H]1[C@@]2 (C[C@]3 (SC2) [C@@H] (O) N4[C@@H] (CC[C@@H] (C) [C@@]4 (CC3) [H]) C=5C=COC5) CC[C@@]6 (N1[C@@H] (CC[C@H]6C) C=7C=COC7) [H]
Molecular Formula
C30H42N2O4S
Molecular Weight
526.73
Storage Conditions
-20°C
Notes
For research use only.
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