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BMI-135

BMI-135 is a selective estrogen mimic, that exhibits agonist activity for estrogen receptor. BMI-135 induces rapid endoplasmic reticulum stress response (UPR) and apoptosis in breast cancer cells[1].

Product Specifications

CAS Number

1608099-90-6

UNSPSC

12352100

Target

Apoptosis; Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Apoptosis; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bmi-135.html

Smiles

O=C(C1=CC=C(C#C)C=C1)C2=C(C3=CC=C(F)C=C3)C4=C(S2)C=C(O)C=C4

Molecular Formula

C23H13FO2S

Molecular Weight

372.41

References & Citations

[1]Abderrahman B, et al., Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer. Mol Cancer Ther. 2021 Jan;20 (1) :11-25.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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