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Aclacinomycin A

Aclacinomycin A (Aclarubicin) is an anthracycline antibiotic derived from Streptomyces galilaeus that acts as a dual topoisomerase I/II inhibitor, suppressing RNA synthesis. Its research applications include studies in relapsed leukemia and advanced lymphomas, utilizing both in vitro and in vivo experimental models to investigate its antitumor mechanisms.

Product Specifications

CAS Number

57576-44-0

Product Name Alternative

Aclarubicin, RNA, Topo II, Topo I

Field of Research

Cell Biology, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry

Purity

99.43% (May vary between batches)

Solubility

DMSO:30 mg/mL (36.95 mM)

Smiles

C (OC) (=O) [C@@H]1C2=C ([C@@H] (O[C@H]3C[C@H] (N (C) C) [C@H] (O[C@H]4C[C@H] (O) [C@H] (O[C@@H]5O[C@@H] (C) C (=O) CC5) [C@H] (C) O4) [C@H] (C) O3) C[C@@]1 (CC) O) C (O) =C6C (=C2) C (=O) C=7C (C6=O) =C (O) C=CC7

Molecular Formula

C42H53NO15

Molecular Weight

811.87

Storage Conditions

-20°C

Notes

For research use only.

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