8-Chloroadenosine-5'-triphosphate sodium
8-Chloro ATP is a bioactive metabolite of the anticancer agent 8-chloro cAMP. It accumulates in cells, depleting endogenous ATP and inhibiting RNA synthesis and topoisomerase IIα activity, as demonstrated in studies using human multiple myeloma and K562 leukemia cell lines.
Product Specifications
CAS Number
793671-47-3
Field of Research
Molecular Biology
Smiles
O[C@@H]1[C@@H] (COP (OP (OP ([O-]) ([O-]) =O) ([O-]) =O) ([O-]) =O) O[C@@H] (N2C3=NC=NC (N) =C3N=C2Cl) [C@@H]1O.[Na+].[Na+].[Na+].[Na+]
Molecular Formula
C10H11ClN5O13P3.4Na
Molecular Weight
629.55
Storage Conditions
-20°C
Notes
For research use only.
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