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Sp-Adenosine-5'-O- (1-thiodiphosphate) sodium

Sp-Adenosine-5’-O- (1-thiodiphosphate) (Sp-ADP-α-S) is a potent phosphorylase kinase inhibitor (Ki=0.53 μM) . This research compound also acts as a platelet aggregator (EC50=20 μM in vitro) and induces smooth muscle relaxation in guinea pig tissue models (EC50=58.9 μM), making it useful for studying purinergic signaling and cellular regulation.

Product Specifications

CAS Number

2005478-90-8

Field of Research

Pharmacology & Drug Discovery

Smiles

O[C@@H]1[C@@H] (CO[P@@] (OP ([O-]) ([O-]) =O) ([S-]) =O) O[C@@H] (N2C3=NC=NC (N) =C3N=C2) [C@@H]1O.[Na+].[Na+].[Na+]

Molecular Formula

C10H12N5O9P2S.3Na

Molecular Weight

509.21

Storage Conditions

-20°C

Notes

For research use only.

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