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Sp-2'-Deoxycytidine-5'-O- (1-thiotriphosphate) sodium

Sp-dCTP-α-S is a stereoisomer of dCTP-α-S that potently inhibits the dNTPase SAMHD1 with a Ki of 6.3 μM. This inhibitor is a valuable research tool for studying SAMHD1's role in nucleotide metabolism, viral restriction, and innate immunity in both cellular and biochemical assays.

Product Specifications

Smiles

O[C@@H] (C1) [C@H] (O[C@H]1N2C=CC (N) =NC2=O) CO[P@@] (OP ([O-]) (OP ([O-]) ([O-]) =O) =O) ([S-]) =O.[Na+].[Na+].[Na+].[Na+]

Molecular Formula

C9H12N3O12P3S.4Na

Molecular Weight

571.10

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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