Sp-2'-Deoxyguanosine-5'-O- (1-thiotriphosphate) sodium
Sp-2'-Deoxyguanosine-5'-O- (1-thiotriphosphate) is a sulfur-modified dGTP analog that potently inhibits the dNTP triphosphohydrolase SAMHD1 with a Ki of 820 nM. This inhibitor is a valuable tool for in vitro studies of SAMHD1's role in nucleotide metabolism, viral restriction, and cancer biology.
Product Specifications
Smiles
O=P (OP ([O-]) ([O-]) =O) ([O-]) O[P@] (OC[C@H]1O[C@@H] (N2C=NC3=C2NC (N) =NC3=O) C[C@@H]1O) ([S-]) =O.[Na+].[Na+].[Na+].[Na+]
Molecular Formula
C10H12N5O12P3S.4Na
Molecular Weight
611.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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