6-hydroxy Buspirone

6-Hydroxy Buspirone is an active CYP3A4-derived metabolite of buspirone. It functions as a 5-HT1A receptor agonist and a potent antagonist of dopamine D2, D3, and D4 receptors, while also inhibiting organic cation transporters (OCT1-3) . This profile makes it a valuable research tool for neuropharmacology studies investigating serotonin and dopamine systems in vitro and in vivo.