Aclacinomycin A HCl
Aclarubicin hydrochloride is an anthracycline antibiotic that inhibits topoisomerase I/II and the 20S proteasome, disrupting DNA processes and generating ROS. It is used in research for studying relapsed leukemia and advanced lymphoma, with applications in both in vitro and in vivo models of oncology and cancer pharmacology.
Product Specifications
CAS Number
75443-99-1
Product Name Alternative
Aclarubicin hydrochloride
Field of Research
Cell Biology, Protein Biochemistry
Purity
>90%
Bioactivity
Proteasome inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml) .
Smiles
C (OC) (=O) [C@@H]1C2=C ([C@@H] (O[C@H]3C[C@H] (N (C) C) [C@H] (O[C@H]4C[C@H] (O) [C@H] (O[C@@H]5O[C@@H] (C) C (=O) CC5) [C@H] (C) O4) [C@H] (C) O3) C[C@@]1 (CC) O) C (O) =C6C (=C2) C (=O) C=7C (C6=O) =C (O) C=CC7.Cl
Molecular Formula
C42H53NO15 HCl
Molecular Weight
848.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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