Beclomethasone 17-propionate
Beclomethasone 17-propionate (17-BMP) is the active glucocorticoid metabolite of beclomethasone dipropionate. With 13-fold greater GR affinity than BDP, it potently suppresses pro-inflammatory cytokines like CXCL8, TNF-α, and IL-6. This mechanism underpins its research applications in studying asthma and allergic rhinitis pathophysiology in both cellular and animal models.
Product Specifications
CAS Number
5534-18-9
Product Name Alternative
17-BMP, Beclomethasone, Beclomethasone 17 propionate, Beclomethasone 17propionate, Beclomethasone 17-propionate, Beclomethasone-17-monopropionate
Field of Research
Metabolism Research
Purity
98.06% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (7.1 mM) ; DMSO:100 mg/mL (215.06 mM)
Smiles
O (C (CC) =O) [C@@]1 (C (CO) =O) [C@]2 (C) [C@@] (C[C@@H]1C) ([C@]3 ([C@] (Cl) ([C@@H] (O) C2) [C@]4 (C) C (CC3) =CC (=O) C=C4) [H]) [H]
Molecular Formula
C25H33ClO6
Molecular Weight
464.98
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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