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Dimethyl-SGD-1882

Dimethyl-SGD-1882 is a potent DNA alkylating agent derived from a pyrrolobenzodiazepine (PBD) dimer. It functions as a cytotoxic payload in antibody-drug conjugates (ADCs), disrupting DNA replication in target cells. Its mechanism is studied in both in vitro cytotoxicity assays and in vivo xenograft models for oncology research.

Product Specifications

CAS Number

3026416-27-0

Smiles

C[C@@]12N (C (C3=CC (OC) =C (OCCCOC4=C (C=C5C (N=C[C@]6 (C) N (C=C (C7=CC=C (OC) C=C7) C6) C5=O) =C4) OC) C=C3N=C2) =O) C=C (C8=CC=C (N) C=C8) C1

Molecular Formula

C44H43N5O7

Molecular Weight

753.84

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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